Endometriosis associates with the increased risk of development of inflammatory diseases of intestines, according to results of the large-scale long-term research which has been carried out by the Danish scientists which are published in on-line release of "Gut" from December 19.
Both endometriosis, and inflammatory diseases of intestines are usually shown by abdominalny pain, as a rule, begin in early adult life, and are chronic inflammatory frustration. In the past the diagnosis of one of diseases excluded the diagnosis of another. However, doctor Tayn Jess (Tine Jess) and colleagues (Statens Serum Institute in Copenhagen, Denmark) have studied national registers to estimate a contributing role of endometriosis concerning development of inflammatory diseases of intestines in women.
Authors have studied patient's records of 37 661 women hospitalised with endometriosis between 1977 and 2007. From these women, at 320 the inflammatory disease of intestines (228 patients have an ulcer colitis, 92 - an illness Krone) has developed. At women with endometriosis the risk of inflammatory diseases of intestines has been increased as a whole (the standardised relation of incidence 1,5), in the same degree, as for ulcer colitis (the standardised relation of incidence 1,5), in comparison with women in the general population. Stratification of patients on groups has shown that the women who have undergone surgical treatment, verifying endometriosis, had increase in risk of inflammatory diseases of intestines at 80 % (ulcer colitis: the standardised relation of incidence 1,8; illness Krone: the standardised relation of incidence 1,7).
Increase of risk remained within 2 decades after the diagnosis of inflammatory diseases of intestines, and the average delay between the diagnosis of endometriosis and development of inflammatory diseases of intestines made about 10 years.
Authors put forward two hypotheses explaining association between 2 frustration: that they have the general base inflammatory basis, or that endometriosis treatment (use of peroralny contraceptives) increases risk of inflammatory diseases of intestines.
«Large-scale not selective kogortny researches are necessary to confirm influence of application of peroralny contraceptives on short-term and long-term risk of inflammatory diseases of intestines, not least in a context of accompanying endometriosis» - scientists conclude.